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Biochemistry news

From receptor structure to new osteoporosis drugs

Researchers at the University of Zurich have determined the three-dimensional structure of a receptor that controls the release of calcium from bones. The receptor is now one of the main candidates for developing new drugs ...

date13 hours ago in Biochemistry
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Scorpion venom to shuttle drugs into the brain

The Peptides and Proteins lab at the Institute for Research in Biomedicine (IRB Barcelona) has published a paper in Chemical Communications describing the use of a peptide derived from chlorotoxin, found in scorpion venom ...

dateNov 15, 2018 in Biochemistry
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Why macrophages rest in healthy tissue

ETH scientists have shown that the immune system's macrophages are regulated not only biochemically, but mechanically as well. This could explain why the cells are less active in healthy body tissue.

dateNov 15, 2018 in Biochemistry
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Synthetic molecule invades double-stranded DNA

Carnegie Mellon University researchers have developed a synthetic molecule that can recognize and bind to double-stranded DNA or RNA under normal physiological conditions. The molecule could provide a new platform for developing ...

dateNov 12, 2018 in Biochemistry
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Bending DNA costs less energy than assumed

The way DNA folds largely determines which genes are read out. John van Noort and his group have quantified how easily rolled-up DNA parts stack. This costs less energy than previously assumed. Publication in Biophysical ...

dateNov 12, 2018 in Biochemistry
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External structure can affect the function of enzymes

A research team from Ruhr-Universität Bochum (RUB) and from South Africa has analysed two enzymes with identical substrate binding pockets that nevertheless convert different substrates. In the process, it emerged that changes ...

RNA microchips

Ribonucleic acid (RNA) is, along with DNA and protein, one of the three primary biological macromolecules and was probably the first to arise in early life forms. In the "RNA world" hypothesis, RNA is able to support life ...

Alcohols as carbon radical precursors

Alcohols play a pivotal role in organic synthesis because they are ubiquitous and can be used in a variety of well-established transformations. However, in C-C bond formation reactions, despite being central to organic synthesis, ...

Remedy against superbacteria found in crowberry

Researchers in Oulu have found small fragments of an antibacterial protein, also known as peptides, in a microbe living in crowberry. The peptide is able to destroy bacteria that cause infections. Based on the peptide, a ...

Physicists explain how large spherical viruses form

A virus, the simplest physical object in biology, consists of a protein shell called the capsid, which protects its nucleic acid genome—RNA or DNA.  The capsid can be cylindrical or conical in shape, but more commonly ...

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Reducing the impact forces of water entry

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